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Abstract—Accurately capturing dynamic scenes with wideranging motion and light intensity is crucial for many vision applications. However, acquiring high-speed high dynamic range (HDR) video is challenging because the camera’s frame rate restricts its dynamic range. Existing methods sacrifice speed to acquire multi-exposure frames. Yet, misaligned motion in these frames can still pose complications for HDR fusion algorithms, resulting in artifacts. Instead of frame-based exposures, we sample the videos using individual pixels at varying exposures and phase offsets. Implemented on a monochrome pixel-wise programmable image sensor, our sampling pattern captures fast motion at a high dynamic range. We then transform pixel-wise outputs into an HDR video using end-to-end learned weights from deep neural networks, achieving high spatiotemporal resolution with minimized motion blurring. We demonstrate aliasing-free HDR video acquisition at 1000 FPS, resolving fast motion under low-light conditions and against bright backgrounds — both challenging conditions for conventional cameras. By combining the versatility of pixel-wise sampling patterns with the strength of deep neural networks at decoding complex scenes, our method greatly enhances the vision system’s adaptability and performance in dynamic conditions. Index Terms—High-dynamic-range video, high-speed imaging, CMOS image sensors, programmable sensors, deep learning, convolutional neural networks.